Sexual Health
PT-141, kisspeptin, melanotan and related peptides.
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PT-141 vs Viagra: differences, evidence and safety
PT-141 (bremelanotide) activates melanocortin receptors and produced erections in small placebo-controlled studies of men, including men Viagra had not helped. Viagra (sildenafil) works on…
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Kisspeptin vs hCG vs Gonadorelin: differences, evidence and safety
Kisspeptin raised LH and testosterone in men for 12 days in a 2026 placebo-controlled study (Yeung 2026). hCG is an FDA-approved prescription hormone for…
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Vyleesi vs Addyi: differences, evidence and safety
Vyleesi (bremelanotide) is an on-demand peptide injection that raised sexual desire scores and cut related distress in two phase 3 trials of 1,267 premenopausal…
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Best peptides for libido: what the evidence shows, tier by tier
The best-researched peptide for libido is bremelanotide (PT-141), sold as Vyleesi. In two phase 3 trials that randomized 1,267 premenopausal women with low sexual…
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PT-141 vs Kisspeptin: differences, evidence and safety
Verdict: PT-141 (bremelanotide) is an FDA-approved drug, Vyleesi, for low sexual desire in premenopausal women, backed by two phase 3 trials. Kisspeptin is not…